AX-024 hydrochloride (Standard)

Overview

AX-024 hydrochloride (Standard) is the analytical standard of AX-024 (hydrochloride) ( HY-107390A ). This product is intended for research and analytical applications. AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC 50 ~1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6 , TNF-α, IFN-γ , IL-10 and IL-17A .

Application

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Product Information

• Catalog No.: HY-107390AR
• CAS No.: 1704801-24-0
• Molecular Formula: C21H23ClFNO2
• Molecular Weight: 375.86
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source