TC-N 1752 (Standard)

Overview

TC-N 1752 (Standard) is the analytical standard of TC-N 1752 ( HY-107405 ). This product is intended for research and analytical applications. TC-N 1752 is a potent and orally active inhibitor of Nav1.7, with IC 50 s of 0.17 μM, 0.3 μM, 0.4 μM, 1.1 μM and 2.2 μM at hNav1.7, hNav1.3, hNav1.4, hNaV1.5 and rNav1.8, respectively. TC-N 1752 also inhibits tetrodotoxin-sensitive sodium channels. TC-N 1752 shows analgesic efficacy in the Formalin model of pain.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-107405R
• CAS No.: 1211866-85-1
• Molecular Formula: C25H27F3N6O3
• Molecular Weight: 516.52
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source