NU6140 (Standard)

Overview

NU6140 (Standard) is the analytical standard of NU6140 ( HY-107419 ). This product is intended for research and analytical applications. NU6140 is a selective CDK2-cyclin A inhibitor (IC 50 , 0.41 μM), exhibits 10- to 36-fold selectivity over other CDKs. NU6140 also potently inhibits Aurora A and Aurora B , with IC 50 s of 67 and 35 nM, respectively. Enhances the apoptotic effect, with anti-cancer activity.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Aurora Kinase

Product Information

• Catalog No.: HY-107419R
• CAS No.: 444723-13-1
• Molecular Formula: C23H30N6O2
• Molecular Weight: 422.52
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source