LDN-211904 oxalate (Standard)

Overview

LDN-211904 oxalate (Standard) is the analytical standard of LDN-211904 (oxalate) ( HY-107460 ). This product is intended for research and analytical applications. LDN-211904 oxalate is a potent and reversible EphB3 inhibitor with an IC 50 of 79 nM. LDN-211904 oxalate shows good metabolic stability in mouse liver microsomes. LDN-211904 oxalate with Cetuximab ( HY-P9905 ) could be effective in inhibiting STAT3-activated colorectal cancer (CRC) stemness and Cetuximab resistance in CRC.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Ephrin Receptor

Product Information

• Catalog No.: HY-107460R
• CAS No.: 1198408-78-4
• Molecular Formula: C21H21ClN4O5
• Molecular Weight: 444.87
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source