8-pCPT-2′-O-Me-cAMP sodium (Standard)

Overview

8-pCPT-2′-O-Me-cAMP sodium (Standard) is the analytical standard of 8-pCPT-2′-O-Me-cAMP (sodium) ( HY-107543 ). This product is intended for research and analytical applications. 8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP) sodium, an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP sodium activates Epac1 (EC 50 = 2.2 μM), but not PKA (EC 50 >10 μM). 8-pCPT-2′-O-Me-cAMP sodium stimulates Epac-mediated Ca2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP sodium is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP sodium enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration.

Application

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Product Information

• Catalog No.: HY-107543R
• CAS No.: 634207-53-7
• Molecular Formula: C17H16ClN5NaO6PS
• Molecular Weight: 507.82
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source