CP-100356 hydrochloride (Standard)

Overview

CP-100356 hydrochloride (Standard) is the analytical standard of CP-100356 (hydrochloride) ( HY-108347 ). This product is intended for research and analytical applications. CP-100356 hydrochloride is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC 50 s of 0.5 and 1.5 µM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 hydrochloride is also a weak inhibitor of OATP1B1 (IC 50 =∼66 µM). CP-100356 hydrochloride is devoid of inhibition against MRP2 and major human P450 enzymes (IC 50 >15 µM).

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > P-glycoprotein | Products > Signaling Pathways > BCRP

Product Information

• Catalog No.: HY-108347R
• CAS No.: 142715-48-8
• Molecular Formula: C31H37ClN4O6
• Molecular Weight: 597.10
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source