MI-2-2 (Standard)

Overview

MI-2-2 (Standard) is the analytical standard of MI-2-2 ( HY-108350 ). This product is intended for research and analytical applications. MI-2-2 is a potent menin-MLL inhibitor. MI-2-2 binds to menin with low nanomolar affinity (K d =22nM) and very effectively disrupts the bivalent protein-protein interaction between menin and MLL. MI-2-2 has specific and very pronounced activity in MLL leukemia cells, including inhibition of cell proliferation, down-regulation of Hoxa9 expression, and differentiation.

Application

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Product Information

• Catalog No.: HY-108350R
• CAS No.: 1454920-20-7
• Molecular Formula: C17H20F3N5S2
• Molecular Weight: 415.50
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source