BL-1249 (Standard)

Overview

BL-1249 (Standard) is the analytical standard of BL-1249 ( HY-108596 ). This product is intended for research and analytical applications. BL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC 50 values of 5.5 μM and 8.0 μM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC 50 of 1.26 μM) than vascular tissue (EC 50 of 21.0 μM).

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-108596R
• CAS No.: 18200-13-0
• Molecular Formula: C17H17N5
• Molecular Weight: 291.35
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source