LY2183240 (Standard)

Overview

LY2183240 (Standard) is the analytical standard of LY2183240 ( HY-10865 ). This product is intended for research and analytical applications. LY2183240 is a highly potent blocker of anandamide uptake (IC 50 = 270 pM; K i =540 nM). LY2183240 is a potent, covalent inhibitor of the endocannabinoid-degrading enzyme fatty acid amide hydrolase ( FAAH ) with an IC 50 of 12.4 nM. LY2183240 inactivates FAAH by carbamylation of the enzyme's serine nucleophile. LY2183240 also inhibits several other brain serine hydrolases with IC 50 s of 5.3, 0.09, 8.2 nM for MAG lipase , bh6 and K i AA1363, respectively .

Application

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Product Information

• Catalog No.: HY-10865R
• CAS No.: 874902-19-9
• Molecular Formula: C17H17N5O
• Molecular Weight: 307.35
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source