SB-334867 free base (Standard)

Overview

SB-334867 free base (Standard) is the analytical standard of SB-334867 (free base) ( HY-10895A ). This product is intended for research and analytical applications. SB-334867 free base (SB334867A free base) is an excellent, selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pK i values of 5.4 and 5.3, respectively. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Orexin Receptor (OX Receptor)

Product Information

• Catalog No.: HY-10895AR
• CAS No.: 792173-99-0
• Molecular Formula: C17H13N5O2
• Molecular Weight: 319.32
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source