Lazertinib (Standard)

Overview

Lazertinib (Standard) is the analytical standard of Lazertinib ( HY-109061 ). This product is intended for research and analytical applications. Lazertinib (YH25448) is a potent, selective, CNS-penetrant, orally available and irreversible EGFR tyrosine K i nase inhibitor, exhibiting high selectivity for activating (EGFRm) and T790M resistance mutations. Lazertinib inhibits phosphorylation of EGFR , AKT and ERK , leading to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models. Lazertinib can be used in the study of non-small cell lung cancer .

Application

Products | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Others | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > TRP Channel | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Akt | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-109061R
• CAS No.: 1903008-80-9
• Molecular Formula: C30H34N8O3
• Molecular Weight: 554.64
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source