Cevidoplenib (Standard)

Overview

Cevidoplenib (Standard) is the analytical standard of Cevidoplenib ( HY-109082 ). This product is intended for research and analytical applications. Cevidoplenib (SK i -O-703) is an orally available inhibitor of spleen tyrosine K i nase ( Syk ), with potential anti-inflammatory and immunomodulating activities. Cevidoplenib is also the mesylate form of SK i -O-592. Cevidoplenib and SK i -O-592 inhibits BCR-mediated survival, proliferation, and differentiation of B cells. And SK i -O-592 potently inhibits multiple K i nases with IC 50 s of 6.2 nM ( Syk ), 1.859 μM ( Jak2 ), 5.807 μM ( Jak3 ), 0.412 μM ( RET ), 0.687 μM (KOR), 1.783 μM ( FLT3 ), 16.96 μM (FGFR1), 5.662 μM (FGFR3), and 0.709 μM ( Pyk2 ), respectively.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Syk

Product Information

• Catalog No.: HY-109082R
• CAS No.: 1703788-21-9
• Molecular Formula: C25H27N7O3
• Molecular Weight: 473.53
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source