Upacicalcet sodium (Standard) is the analytical standard of Upacicalcet (sodium) ( HY-109106A ). This product is intended for research and analytical applications. Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC 50 = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine ( HY-B0152 )-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic K i dney disease (CK d ). Upacicalcet sodium is useful for studying SHPT.
Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > CaSR
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