Lorpucitinib (Standard) is the analytical standard of Lorpucitinib ( HY-109182 ). This product is intended for research and analytical applications. Lorpucitinib (JNJ-64251330) is an orally active pan-JAK inhibitor. Lorpucitinib inhibits all four human JAKs, with greatest potency toward JAK1 / JAK3 and JAK1 / TYK2 heterodimers, and reduces STAT-3 phosphorylation downstream of JAK signaling. Lorpucitinib can be used for the research of gastrointestinal inflammatory diseases.
Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > JAK | Products > Signaling Pathways > STAT
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