SW208108

Overview

SW208108 is a prodrug of dMe-SW208108, a CYP4F11-activated SCD inhibitor, with an IC 50 value of 9 nM. SW208108 undergoes demethylation by CYP4F11 to form the active metabolite dMe-SW208108, thereby inhibiting enzyme function. SW208108 depletes unsaturated fatty acids, induces cytotoxicity in non-small cell lung cancer (NSCLC) cells expressing CYP4F11, and does not affect SCD activity in mouse sebocytes. SW208108 can be used in studies related to NSCLC.

Application

Products | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Stearoyl-CoA Desaturase (SCD) | Products > Signaling Pathways > Drug Intermediate

Product Information

• Catalog No.: HY-114606
• CAS No.: 1673557-43-1
• Molecular Formula: C27H24N2O5
• Molecular Weight: 456.50
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source