Leptophos oxon, a metabolite of leptophos, is a GABA A receptor chloride channel inhibitor with an IC 50 values of 89.6 μM. Leptophos oxon inhibits GABA-induced chloride influx, binds to GABA A receptor-associated TBPS sites, and inhibits TBPS binding to voltage-dependent chloride channels. Leptophos oxon is a insecticide . Leptophos oxon can be used for the research of neurological disease .
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