2-Deoxy-2-fluoro-L-fucose (GMP)

2-Deoxy-2-fluoro-L-fucose (GMP)
  • CAS No.:70763-62-1
  • Formula:C6H11FO4
  • M.W.:166.15

Overview

2-Deoxy-2-fluoro-L-fucose (2-Fluorofucose) GMP is a fucosyltransferase inhibitor that inhibits core fucosylation modification in cells. 2-Deoxy-2-fluoro-L-fucose GMP promotes the production of defucosylated IgG1 antibodies in IgG1-expressing cell culture systems; it regulates the levels of inflammatory cytokines such as IL-1β, IL-6 and TGF-β in human induced pluripotent stem cell-derived microglia. 2-Deoxy-2-fluoro-L-fucose GMP can be used in the research of related diseases including dengue fever and Alzheimer's disease.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Viral Infection | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Infection | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Glycosyltransferase

Product Information

  • Catalog No.: HY-116705G
  • CAS No.: 70763-62-1
  • Molecular Formula: C6H11FO4
  • Molecular Weight: 166.15
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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