NEU-4438 is an antimalarial agent. NEU-4438 inhibits DNA synthesis, reduces AMPK-γ , and increases Clathrin heavy chain. NEU-4438 exhibits antiparasitic activity against Trypanosoma brucei . NEU-4438 reduces trypanosome tissue burden in a chronic HAT mouse model.
Products | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Trypanosome Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Infection | Products > Signaling Pathways > Clathrin | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > AMPK
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