ToP-DNJ is a selective endoplasmic reticulum α-glucosidase II ( GluII ) inhibitor with an IC 50 value of 9.0 μM. ToP-DNJ selectively inhibits the two catalytic reactions of GluII , and exhibits stronger activity in the first step of converting di-glycosylated glycans to mono-glycosylated glycans. ToP-DNJ exhibits anti- DENV activity. ToP-DNJ can be used in studies related to dengue virus infection .
Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Disease Areas > Flavivirus Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Glycosidase | Products > Signaling Pathways > Dengue Virus
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