Fenaminosulf is a plant immune modulator and mutagen. Fenaminosulf impairs plant immune recognition and signal transduction by inhibiting the activities of key kinases such as Xa21 and PBL19 , thereby regulating the expression of genes related to hormone metabolism, phenylpropane biosynthesis, and plant-pathogen interactions. Fenaminosulf affects the growth and gall formation of Zizania latifolia in a concentration-dependent manner. Fenaminosulf induces mutations in bacterial systems and causes plant chromosome aberrations, but shows no mutagenic activity or lethal effect in Drosophila melanogaster. Fenaminosulf exhibits inconsistent carcinogenicity in rat studies.
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