Clozapine-d 11

Overview

Clozapine -d 11 (HF 1854-d 11 ) is the deuterium labeled Clozapine ( HY-14539 ). Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC 50 = 11 nM).

Application

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Product Information

• Catalog No.: HY-14539S5
• CAS No.: 1233341-42-8
• Molecular Formula: C18H8D11ClN4
• Molecular Weight: 337.89
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source