ADAMTS-4/5-IN-1

Overview

ADAMTS-4/5-IN-1 is an orally active, and selective dual ADAMTS-4 / 5 inhibitor with IC 50 values of 2 nM for human ADAMTS-4 and human ADAMTS-5 , respectively. ADAMTS-4/5-IN-1 exhibits high selectivity against MMP enzymes . ADAMTS-4/5-IN-1 reduces aggrecan degradation products in synovial fluid. ADAMTS-4/5-IN-1 can be used for the research of osteoarthritis.

Application

Products | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Osteoarthritis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ADAMTS

Product Information

• Catalog No.: HY-153505
• CAS No.: 1607004-34-1
• Molecular Formula: C20H22F3N3O3
• Molecular Weight: 409.40
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source