MK-2305

Overview

MK-2305 is an orally active GPR40 partial agonist with an EC 50 of 6 nM in rats. MK-2305 mediates glucose-stimulated insulin secretion and inhibits endogenous glucose production by reducing gluconeogenesis from tricarboxylic acid (TCA) cycle substrates. MK-2305 increases plasma insulin levels under hyperglycemic and glucose-stimulated conditions, reduces fasting blood glucose, and improves glucose homeostasis. MK-2305 can be used in studies related to type 2 diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Type 2 Diabetes | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Free Fatty Acid Receptor

Product Information

• Catalog No.: HY-153667
• CAS No.: 2101206-49-7
• Molecular Formula: C19H13ClF3NO4S
• Molecular Weight: 443.82
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source