Val-Cit-Exatecan

Overview

Val-Cit-Exatecan is a peptide-linked anti-tumor payload that can be used for the synthesis of antibody-drug conjugates ( ADC ). Val-Cit-Exatecan consists of DNA TopI inhibitor Exatecan ( HY-13631 ) and a cathepsin-cleavable ADC linker (valine-citrulline). Val-Cit-Exatecan can be used in the research of colorectal cancer , gastric cancer , breast cancer , non-small cell lung cancer , ovarian cancer , head and neck cancer , pancreatic cancer , cervical cancer , and melanoma.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Drug-Linker Conjugates for ADC | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-160756
• CAS No.: 2952679-21-7
• Molecular Formula: C38H47FN8O9
• Molecular Weight: 778.83
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source