ASB16165

Overview

ASB16165 is a selective and potent PDE7A inhibitor with an IC 50 of 15 nM against human PDE7A. ASB16165 inhibits IL-12-induced IFN-γ production via a cAMP/PKA -dependent mechanism, reduces cutaneous TNF-α production, and suppresses keratinocyte proliferation. ASB16165 can be used in research on skin diseases such as psoriasis.

Application

Products | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Skin Inflammation | Products > Disease Areas > Psoriasis | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > PKA | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-165553
• CAS No.: 873541-45-8
• Molecular Formula: C23H29N5O2S
• Molecular Weight: 439.58
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source