GSK1370319A

Overview

GSK1370319A is a human P2X7 receptor inhibitor with an IC 50 of 474 nM and a K i of 176 nM. GSK1370319A inhibits the production of IL-1β , reduces the generation of reactive oxygen species ( ROS ), and increases the survival rate of macrophages. GSK1370319A can be used for the research of inflammatory bowel disease.

Application

Products | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Inflammatory Bowel Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > P2X Receptor | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-165557
• CAS No.: 1001389-31-6
• Molecular Formula: C13H14Cl2N2O2
• Molecular Weight: 301.17
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source