WWQ-131

Overview

WWQ-131 is a potent selective JAK2 inhibitor with an IC 50 of 2.56 nM. WWQ-131 shows >252-fold selectivity over JAK1 , JAK3 , and TYK2 . WWQ-131 exhibits antiproliferative activity against cancer cells. WWQ-131 is the ligand for target protein for PROTAC JAK2 degrader-1 ( HY-174428 ). WWQ-131 can be used for the research of myeloproliferative neoplasms (MPNs).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ligands for Target Protein for PROTAC | Products > Signaling Pathways > JAK

Product Information

• Catalog No.: HY-174430
• CAS No.: 1558007-80-9
• Molecular Formula: C21H23ClFN5O
• Molecular Weight: 415.89
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source