PROTAC EZH2 Degrader-12

Overview

PROTAC EZH2 Degrader-12 (compound 3) is a CRBN -recruiting PROTAC-based EZH2 degrader with an EZH2 IC 50 of 3.90 nM and EZH1 IC 50 of 5.24 μM. (Pink: EZH2 ligand ( HY-13470 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-181307
• CAS No.: 2653338-62-4
• Molecular Formula: C50H58N8O7
• Molecular Weight: 883.04
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source