PROTAC EZH2 Degrader-19

Overview

PROTAC EZH2 Degrader-19 (compound 6) is a is a PROTAC protein degrader targeting EZH2 with an IC 50 of 15.00 nM. PROTAC EZH2 Degrader-19 induces strong degradation of all PRC2 subunits ( EZH2 , SUZ12 , EED , RbAp48 ) in a concentration- and time-dependent manner.PROTAC EZH2 Degrader-19 exhibits antiproliferative effects in cancer cells.PROTAC EZH2 Degrader-19 can be used for the research of cancer . (Pink: EZH2 ligand ( HY-13470 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-181320
• CAS No.: 2653338-65-7
• Molecular Formula: C53H64N8O7
• Molecular Weight: 925.12
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source