PROTAC EZH2 Degrader-26

Overview

PROTAC EZH2 Degrader-26 (compound 11) is an EZH2 degrader developed based on PROTAC technology. PROTAC EZH2 Degrader-26 has an IC 50 of 5.80 nM against EZH2 . PROTAC EZH2 Degrader-26 exhibits micromolar-level enzyme inhibitory activity against EZH1 , with an EZH1 IC 50 of 0.06 μM. (Pink: EZH2 ligand ( HY-147230 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker).

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Others | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-181327
• CAS No.: 2641601-66-1
• Molecular Formula: C52H63N7O8
• Molecular Weight: 914.10
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source