PROTAC EZH2 Degrader-38

Overview

PROTAC EZH2 Degrader-38 (Compound 17) is a EZH2 PROTAC degrader with an IC 50 of 165.00 nM. PROTAC EZH2 Degrader-38 functionally inhibits the methyltransferase activity of EZH2 and competitively binds to the SAM-binding pocket of the EZH2 SET domain. (Pink: EZH2 ligand ( HY-147230 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker).

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Others | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-181333
• CAS No.: 2653338-74-8
• Molecular Formula: C58H75N7O8
• Molecular Weight: 998.26
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source