PROTAC EZH2 Degrader-39 (compound 18) is a PROTAC protein degrader targeting EZH2 with a target IC 50 of 61.00 nM. PROTAC EZH2 Degrader-39 functionally inhibits EZH2 methyltransferase activity. (Pink: EZH2 ligand ( HY-147230 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker).
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