Antibacterial agent 327

Overview

Antibacterial agent 327 (Compound 6f) is an Antibacterial agent. Antibacterial agent 327 potently inhibits the supercoiling activity of Staphylococcus aureus DNA gyrase with an IC 50 of 0.28 μM. It also inhibits the ATPase activities of DNA gyrase and Topoisomerase IV , as well as the decatenation activity of Topoisomerase IV (IC 50 : 0.43 μM, 0.73 μM, and 2.31 μM, respectively). Antibacterial agent 327 potently inhibits Clostridioides difficile and methicillin-resistant Staphylococcus aureus ( HY-121544 ), with an MIC of 0.78 μg/mL for both. Antibacterial agent 327 inhibits Escherichia coli with an MIC 50 of 0.78 μg/mL.

Application

Products | Products > Disease Areas > Clostridium Difficile Infection | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Disease Areas > Escherichia Coli Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-181819
• CAS No.: 1311163-39-9
• Molecular Formula: C34H42ClN3O17S
• Molecular Weight: 832.23
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source