IRBM-Z-2

Overview

IRBM-Z-2 is a non-competitive, orally active Zika virus ( ZIKV ) NS2B-NS3 protease inhibitor, with IC 50 values of 0.04 μM and 3.1 μM against the wild-type and I156T mutant strains, respectively. IRBM-Z-2 exhibits broad-spectrum anti-flavivirus potential, with IC 50 values of 2.1 μM and 0.09 μM against the NS2B-NS3 proteases of dengue virus 2 (DENV2) and West Nile virus (WNV), respectively. IRBM-Z-1 inhibits ZIKV replication and alleviates virus-induced cytopathic effects. IRBM-Z-1 can be used in studies related to ZIKV infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Disease Areas > Flavivirus Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Virus Protease | Products > Signaling Pathways > Flavivirus

Product Information

• Catalog No.: HY-181991
• CAS No.: 3014840-61-7
• Molecular Formula: C22H18F3N7O2
• Molecular Weight: 469.42
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source