Triflocin

Overview

Triflocin is an orally active diuretic and Na + -K + -2Cl − cotransporter inhibitor with an IC 50 of 3×10 -5 M. Triflocin inhibits the outward basolateral electrogenic Na-(HCO3) n>1 cotransport in the proximal tubule. Triflocin has no tendency to induce hyperglycemia, and its blood glucose-elevating effect is extremely weak, such that an increase in blood glucose levels can only be detected under special conditions such as glucose loading. Triflocin is more prone to induce hypoglycemia.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Urologic Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > NKCC

Product Information

• Catalog No.: HY-182386
• CAS No.: 13422-16-7
• Molecular Formula: C13H9F3N2O2
• Molecular Weight: 282.22
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source