TSI-13-48 ( HY-182409 ) is a TLR inhibitor with IC 50 values of 3.02, 22.3, 26.5, and 26.6 μM against TLR9 , TLR7 , TLR2 , and TLR4 , respectively. TSI-13-48 can be used in research related to systemic lupus erythematosus, polymicrobial sepsis, and cerebral malaria.
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