Product

1-(4-HYDROXYPHENYL)-2-THIOUREA

CAS No.：1520-27-0

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1-(4-HYDROXYPHENYL)-2-THIOUREA Basic information

Product Name:	1-(4-HYDROXYPHENYL)-2-THIOUREA
Synonyms:	4-HYDROXYPHENYLTHIOUREA;1-(4-HYDROXYPHENYL)-2-THIOUREA;4-HYDROXYPHENYLTHIOUREA, 98+%;USAF B-75;1-(p-hydroxyphenyl)-2-thio-ure;p-hydroxyphenylthiourea;1-(4-hydroxyphenyl)thiourea;N-(4-Hydroxyphenyl)thiourea
CAS:	1520-27-0
MF:	C7H8N2OS
MW:	168.22
EINECS:
Product Categories:
Mol File:	1520-27-0.mol

1-(4-HYDROXYPHENYL)-2-THIOUREA Chemical Properties

Melting point	214 °C
storage temp.	2-8°C
BRN	1102429
CAS DataBase Reference	1520-27-0(CAS DataBase Reference)

Safety Information

Risk Statements	22
Safety Statements	22-36/37
RTECS	YT5250000
HazardClass	IRRITANT

MSDS Information

Provider	Language
ALFA	English

1-(4-HYDROXYPHENYL)-2-THIOUREA Usage And Synthesis

Uses	1-(4-Hydroxyphenyl)thiourea is an intermediate in the synthesis of (SKI II), a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.

1-(4-HYDROXYPHENYL)-2-THIOUREA Preparation Products And Raw materials

Raw materials

N-Benzoyl-N'-(p-hydroxyphenyl)thiourea-->Thiourea, N,N'-bis(4-hydroxyphenyl)--->(4-Hydroxyphenyl)dithiocarbamicacid,triethylaminesalt-->4-HYDROXYPHENYLISOTHIOCYANATE-->Benzoyl isothiocyanate-->4-Hydroxyaniline hydrochloride-->Potassium thiocyanate-->Sodium thiocyanate-->4-Aminophenol

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