Siccayne, found in the marine basidiomycete Halocyphina villosa and deuteromycete Helminthosporium siccans , is an antibiotic . Siccayne interferes with nucleotide incorporation into DNA and RNA, precursor transport enzymatic reactions, and essential macromolecule synthesis. Siccayne inhibits Gram-positive bacteria and some fungi . Siccayne can be used for research on infections caused by bacteria and fungi.
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