Deoxaphomin is a cytochalasin. Deoxaphomin inhibits Actin filament elongation and reduces the viscosity of polymerized actin filaments. Deoxaphomin induces rounding of fibroblasts, contraction of actin cables, formation of actin-containing hairy structures, and formation of actin-containing cytoplasmic rodlets in fibroblasts. Deoxaphomin inhibits membrane ruffling in fibroblasts and capping in lymphocytes.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Arp2/3 Complex
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