BO-653 is an orally active anti-atherosclerotic antioxidant that exhibits high binding affinity for LDL . BO-653 scavenges linoleic acid peroxyl radicals, inhibits lipid peroxidation during the auto-oxidation of linoleic acid, and potently suppresses LDL oxidation. BO-653 inhibits Hepatitis C Virus ( HCV ) replication in a concentration-dependent manner, with an IC 50 of 36.0 μM against the HCV subgenomic replicon in FLR3-1 cells. BO-653 demonstrates significant anti-atherosclerotic effects in various animal models, including the Watanabe heritable hyperlipidemic rabbit. BO-653 is suitable for use in research related to atherosclerosis and Hepatitis C Virus infection .
Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Hepatitis Virus Infection | Products > Disease Areas > Chronic Disease and Inflammation | Products > Disease Areas > Hepatitis C Virus Infection | Products > Disease Areas > Atherosclerosis and Inflammation | Products > Signaling Pathways > Others | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > HCV
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.