VGD020

Overview

VGD020 is a highly potent and selective Sec61 translocon inhibitor . VGD020 suppresses the expression of cell surface CD4 by inhibiting signal peptide-dependent co-translational ER translocation, interferes with the initiation of ER translocation of dengue virus polyprotein, and reduces the expression of Sortilin in breast cancer cells. VGD020 exhibits broad anti-flavivirus and anti-HIV activities. VGD020 can be used in research related to dengue virus infection , Zika virus infection , yellow fever virus infection , human immunodeficiency virus infection , and breast cancer .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Sec61 | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > Neurotensin Receptor

Product Information

• Catalog No.: HY-182674
• CAS No.: 1322645-32-8
• Molecular Formula: C31H45N3O5S2
• Molecular Weight: 603.84
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source