MMV675968

Overview

MMV675968 is an inhibitor of Acinetobacter baumannii dihydrofolate reductase ( AbDHFR ) with an IC 50 of 8.5 nM, and it exhibits selectivity against human DHFR. MMV675968 inhibits dihydrofolate reductase in Cryptosporidium , Plasmodium , and Escherichia coli , disrupting the thymidylate cycle and folate biosynthesis pathway. MMV675968 inhibits the growth of multiple A. baumannii strains, including clinical isolates and environmental isolates. MMV675968 is applicable to research related to A. baumannii infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Dihydrofolate reductase (DHFR)

Product Information

• Catalog No.: HY-182684
• CAS No.: 159308-73-3
• Molecular Formula: C17H18ClN5O2
• Molecular Weight: 359.81
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source