LY3358966

Overview

LY3358966 is an orally active sodium-dependent phosphate cotransporter 2b ( NPT2b ) inhibitor with a human IC 50 of 32.4 nM, mouse IC 50 of 43.9 nM, and rat of IC 50 26.8 nM. LY3358966 inhibits NPT2b-mediated intestinal phosphate transport, decreases acute phosphate uptake into plasma, and increases fecal phosphate excretion. LY3358966 can be used for the research of renal disease.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Renal Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Sodium Phosphate Cotransporter

Product Information

• Catalog No.: HY-182689
• CAS No.: 2187395-66-8
• Molecular Formula: C43H49F2N5O6S
• Molecular Weight: 801.94
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source