NHWL071065

Overview

NHWL071065 is a CRBN -targeting IKZF1 / IKZF3 molecular glues degrader. NHWL071065 selectively degrades IKZF1 and IKZF3 in lymphoma cells via the ubiquitin-proteasome pathway. NHWL071065 inhibits the proliferation of lymphoma cells. NHWL071065 downregulates proteins involved in cytoskeleton assembly, cell adhesion and immune regulation in cells, while upregulating proteins related to the type I IFN signaling pathway. NHWL071065 can be used in the research of lymphoma.

Application

Products | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > IKZF Family | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-182797
• CAS No.: 3117340-01-6
• Molecular Formula: C31H37FN6O4
• Molecular Weight: 576.66
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source