ND-011458 is an Antibacterial agent, a QcrB inhibitor, and also an inhibitor of cytochrome bcc:aa3 oxidase function. ND-011458 binds to the QcrB subunit of cytochrome bcc:aa3 oxidase. ND-011458 inhibits ATP formation. When used in combination with Clofazimine ( HY-B1046 ), ND-011458 exhibits bactericidal activity against Mycobacterium abscessus . ND-011458 can be used in studies related to Mycobacterium abscessus pulmonary infections.
Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > ATP Synthase
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