R 8231 is a reversible inhibitor of Alkaline Phosphatase. R 8231 potently inhibits alkaline phosphatases derived from human liver, bone, kidney and spleen, while exerts weak effects on those derived from human intestine and placenta. The IC50 value of R 8231 for inhibiting bone alkaline phosphatase from adult rabbits is approximately 1 μM, whereas that for inhibiting chicken bone alkaline phosphatase is approximately 100 μM. R 8231 can be used for alkaline phosphatase histochemistry, phosphatase activity identification and bone metabolism-related studies. - Mechanism of Action & Protocol.
Products | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phosphatase
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