ALK5 ligand-1

Overview

ALK5 ligand-1 (a31's ALK5 ligand) is a ligand of Anaplastic lymphoma kinase ALK5 with higher selectivity for ALK5 than for ALK4 . ALK5 ligand-1 can be used to synthesize PROTAC degraders targeting ALK5 . ALK5 PROTACs induce ALK5 degradation dependent on the ubiquitin-proteasome system and exert antifibrotic activity. ALK5 ligand-1 can be used in studies of pulmonary fibrosis.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Ligands for Target Protein for PROTAC | Products > Signaling Pathways > Anaplastic lymphoma kinase (ALK)

Product Information

• Catalog No.: HY-183441
• CAS No.: 3125240-66-3
• Molecular Formula: C20H14ClFN4O3
• Molecular Weight: 412.80
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source