PROTAC ALK5 Degrader-1

Overview

PROTAC ALK5 Degrader-1 is a selective ALK5 PROTAC degrader. PROTAC ALK5 Degrader-1 induces ALK5 degradation via ALK5 ATP-binding pocket engagement, CRBN recruitment, and the ubiquitin-proteasome system. PROTAC ALK5 Degrader-1 inhibits ALK5 downstream signaling. PROTAC ALK5 Degrader-1 can be used for the research of pulmonary fibrosis. (Pink: Anaplastic lymphoma kinase (ALK) ligand ( HY-183441 ); Blue: Cereblon ligand ( HY-14658 ); Black: linker ( HY-183440 )).

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Anaplastic lymphoma kinase (ALK)

Product Information

• Catalog No.: HY-183785
• CAS No.: 3125240-35-6
• Molecular Formula: C43H43ClFN9O7
• Molecular Weight: 852.31
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source