Tyrphostin AG 537

Overview

Tyrphostin AG 537 is a dynamin I GTPase inhibitor with an IC 50 of 1.7 μM. Tyrphostin AG 537 inhibits phospholipid-stimulated GTPase activity without competing for the GTP domain or PH domain of dynamin I. Tyrphostin AG 537 inhibits spermidine-induced autoactivation of pro-plasma hyaluronan-binding protein (pro-PHBP) with an IC 50 of 0.018 μM. Tyrphostin AG 537 can be used in inflammation-related research.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Dynamin

Product Information

• Catalog No.: HY-184059
• CAS No.: 140674-77-7
• Molecular Formula: C23H20N4O6
• Molecular Weight: 448.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source