PROTAC HPK1 Degrader-8

Overview

PROTAC HPK1 Degrader-8 is a HPK1 PROTAC degrader with a DC 50 of 1-10 nM. PROTAC HPK1 Degrader-8 promotes HPK1 ubiquitination and degradation. PROTAC HPK1 Degrader-8 induces IL-2 production, with an EC 50 of 3 nM. PROTAC HPK1 Degrader-8 can be used in research related to hematologic malignancies and solid tumors. (Pink: HPK1 Target protein ligand; Blue: Cereblon ligand ( HY-W115490 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > MAP4K | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-184230
• CAS No.: 3120899-50-2
• Molecular Formula: C39H40ClN9O3
• Molecular Weight: 718.25
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source